The major goal in the Martin group is to provide solutions to relevant and challenging synthetic problems from the scientific and industrial standpoint, without losing sight its environmental impact. In order to meet these challenges, the group is mainly focused on the metal-catalyzed, selective activation of relatively inert entities of great significance, such as CO2, C-H bonds, C-C bonds and C-O bonds, as these motifs rank amongst the most widespread and fundamental linkages in organic chemistry. We are also interesting on the design and implementation of metal-catalyzed domino reactions since a high degree of molecular complexity can be achieved in a one-step, hence allowing a rapid access to key backbones occurring in many natural products.
- Ni-catalyzed Functionalization of C-N Bonds
- Pd-catalyzed C-H Activation
- Ni-catalyzed CO2 Activation
- Catalytic Reductive Amidation
“Alkyl bromides as mild hydride sources in Ni-catalyzed hydroamidation of alkynes with isocyanates”
Am. Chem. Soc. 2016, 138, 15531-15534
Wang, X. ; Nakajima, M. ; Serrano, E.; Martin, R.
“Phenol derivatives: modern electrophiles in cross-coupling reactions”
Adv. Organomet. Chem. 2016, 66, 143-222
Zarate, C.; van Gemmeren, M.; Somerville, R.; Martin, R.
“Ipso-borylation of aryl ethers via Ni-catalyzed C-OMe cleavage”
J. Am. Chem. Soc. 2016, 137, 6754-6757
Wang, X.; Gallardo-Donaire, J.; Martin, R.
“Metal-catalyzed carboxylation of organic (pseudo)halides with CO2”
ACS Catal. 2016, 6, 6739-6749
Börjesson, M.; Moragas, T.; Gallego, D.; Martin, R.
“Ni- and Fe-catalyzed carboxylation of unsaturated hydrocarbons with CO2”
Top. Curr. Chem. 2016, 374:45
Juliá-Hernández, F.; Gaydou, M.; Serrano, E.; van Gemmeren, M.; Martin, R.
“Nickel-catalyzed reductive carboxylation of cyclopropyl motifs with carbon dioxide”
Synthesis 2016, 48, 2816-2822
Moragas, T.; Martin, R.
“Nickel-catalyzed reductive amidation of unactivated alkyl bromides”
Angew. Chem. Int. Ed. 2016, 55, 11207-11211
Serrano, E.; Martin, R.
“Ni-catalyzed carboxylation of unactivated alkyl chlorides with CO2”
J. Am. Chem. Soc. 2016, 138, 7504-7507
Börjesson, M; Moragas, T.; Martin, R.
“Pd-catalyzed C(sp3)-H functionalization/carbenoid insertion: All-carbon quaternary centers via multiple C-C bond-formation”
J. Am. Chem. Soc. 2016, 138, 6384
Gutiérrez-Bonet, A.; Juliá-Hernández, F.; de Luis, B.; Martin, R.
“Nickel-catalyzed carboxylation of benzylic C-N bonds with CO2”
Angew. Chem. Int. Ed. 2016, 55, 5053-5057
Moragas, T.; Gaydou, M.; Martin, R.