Pericàs
Research group
Abstract
Over the last years, the Pericàs laboratory at ICIQ has been engaged in a broad research program aimed at developing a complete toolkit of polymer-supported and magnetic nanoparticle-immobilized catalysts with optimized characteristics of catalytic activity, high induced stereoselectivity and extended life cycle.
The ultimate goal of this research has been the development of single-pass, catalytic and enantioselective flow versions of the most relevant processes for organic synthesis, contributing in this manner to a more sustainable practice of chemical synthesis. Our laboratory at ICIQ has been pioneer in this effort, being recognized as one of the leaders in the field.
Topics addressed
- Supported organocatalysts and flow processes
- Metal-catalyzed transformations and flow processes
- Enantioselective homogeneous organo-catalysis
Articles
“Organocatalytic Enantioselective Continuous-Flow Cyclopropanation”
Org. Lett. 2016, 18,6292-6295.
P. Llanes, C. Rodríguez-Escrich, S. Sayalero, M. A. Pericàs
“Concentration Effect in the Asymmetric Michael Addition of Acetone to β-Nitrostyrenes Catalyzed by Primary Amine Thioureas”
Synthesis (Germany) 2016, 49, 319-325
Z.I. Günler, I. Alfonso, C. Jimeno, M.A. Pericàs
“Key Non-Metal Ingredients for Cu-catalyzed “Click” Reactions in Glycerol: Nanoparticles as Efficient Forwarders”
Chem. Eur. J. 2016, 22,18247-18253
M. Rodríguez-Rodríguez, P. Llanes, C. Pradel, M. A. Pericàs, M. Gómez
“Polystyrene-Supported TRIP: A Highly Recyclable Catalyst for Batch and Flow Enantioselective Allylation of Aldehydes”
ACS Catalysis 2016, 6 (11), 7647–7651
L. Clot-Almenara, C. Rodríguez-Escrich, L. Osorio-Planes, M. A. Pericàs
“Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches”
Nature Communications 2016, 7, 12221
M. Izquierdo-Serra, A. Bautista-Barrufet, A. Trapero, A. Garrido-Charles, A. Díaz-Tahoces, N. Camarero, S. Pittolo, S. Valbuena, A. Pérez-Jiménez, M. Gay, A. García-Moll, C. Rodríguez-Escrich, J. Lerma, P. de la Villa, E. Fernandez, M. A. Pericàs, A. Llebaria, P. Gorostiza
“Deciphering the roles of multiple additives in organocatalyzed Michael additions”
Chem. Commun. 2016, 52, 6821-6824.
Z. I. Günler, X. Companyó, I. Alfonso, J. Burés, C. Jimeno, M. A. Pericàs
“Removing the superfluous: a supported squaramide catalyst with a minimalistic linker applied to the enantioselective flow synthesis of pyranonaphthoquinones”
Catal. Sci. Technol. 2016, 6, 4686-4689.
L. Osorio-Planes, C. Rodríguez-Escrich, M. A. Pericàs
“Asymmetric cross- and self-aldol reactions of aldehydes in water with a polystyrene-supported triazolylproline organocatalyst”
Green Chem. 2016, 18, 3507-3512.
P. Llanes, S. Sayalero, C. Rodríguez-Escrich, M. A. Pericàs
“Synthesis and Application of Magnetic Noyori-Type Ruthenium Catalysts for Asymmetric Transfer Hydrogenation Reactions in Water”
ACS Sustainable Chem. Eng. 2016, 4, 2698-2705.
C. M. Eichenseer, B. Kastl, M. A. Pericàs, P. R. Hanson, O. Reiser
“Polystyrene or Magnetic Nanoparticles as Support in Enantioselective Organocatalysis? A Case Study in Friedel-Crafts Chemistry”
Org. Lett. 2016, 18, 1602-1605.
S. Ranjbar, P. Riente, C. Rodríguez-Escrich, J. Yadav, K. Ramineni, M. A. Pericàs
“H-Bond-Directing Organocatalyst for Enantioselective [4+2] Cycloadditions via Dienamine Catalysis”
Org. Lett. 2016, 18, 556-559.
S. Wang, C. Rodriguez-Escrich, M. A. Pericàs
“Synthesis and catalytic applications of C3-symmetric tris(triazolyl)methanol ligands and derivatives”
Chem. Commun. 2016, 52, 1997-2010
P. Etayo, C. Ayats, M. A. Pericàs
“A Recyclable, Immobilized Analogue of Benzotetramisole for Catalytic Enantioselective Domino Michael Addition/Cyclization Reactions in Batch and Flow”
ACS Catal. 2016, 6, 348-356.
J. Izquierdo, M. A. Pericàs